AG-13958
CAS No. : 319460-94-1
(Synonyms: AG-013958)
| Size | Price | Stock |
|---|---|---|
| 1mg | $120 | In-stock |
| 5mg | $340 | In-stock |
| 10mg | $520 | In-stock |
| 25mg | $850 | In-stock |
| 50mg | $1200 | In-stock |
| 100mg | $1600 | In-stock |
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| Cat. No. : | HY-15492 |
| M.Wt: | 467.50 |
| Formula: | C26H22FN7O |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1]. In Vitro:AG-13958 (AG-013958) is ATP-competitive by tight-binding kinetic analysis when minigastrin (0.5 mM) is used as a substrate[2]. In Vivo:ST administration (Steroid injection) of AG-13958 suspension produces a depot of drug on the posterior surface of the sclera that provided sustained exposure to the choroid with little impact on peripheral tissues and no measurable systemic exposure[1].
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