LY-466195
CAS No. : 317844-33-0
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| Cat. No. : | HY-19858 |
| M.Wt: | 346.37 |
| Formula: | C16H24F2N2O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
LY-466195 is a selective and competitive GLUK5 receptor antagonist. LY-466195 antagonizes Kainate-induced currents with an IC50 value of 0.045 μM in rat dorsal root ganglion neurons. In HEK293 cells transfected with GLUK5, GLUK2/GLUK5, or GLUK5/GLUK66 receptors, LY466195 produces IC50 values of 0.08 μM, 0.34 μM, and 0.07 μM, respectively[1].
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