Opipramol
CAS No. : 315-72-0
(Synonyms: Ensidon; G-33040)
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $75 | In-stock |
| 25mg | $150 | In-stock |
| 50mg | $250 | In-stock |
| 100mg | $375 | In-stock |
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| Cat. No. : | HY-118901 |
| M.Wt: | 363.50 |
| Formula: | C23H29N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD)[1][2].
IC50 & Target:Ki: 50 nM (σ receptor); IC50: 5.5 μM ([3H] DA)[1].
In Vitro:Opipramol can potently interact with sigma recognition sites with a Ki value of 50 nM[1].
Opipramol inhibit the uptake of [3H] DA in crude synaptosomal preparations with an IC50 value of 5.5 μM[1].
In Vivo:Opipramol (i.p.; 5-50 mg/kg) increases dopamine release in vivo[2].
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