| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $160 | In-stock |
| 50mg | $240 | In-stock |
| 100mg | $360 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-17550 |
| M.Wt: | 246.30 |
| Formula: | C14H18N2O2 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic);DMSO : ≥ 2.6 mg/mL |
Sunifiram (DM-235) is an ampakine-like compound and an agonist of AMPA receptor with oral activity. Sunifiram can increase the release of acetylcholine in the rat cerebral cortex and exhibits potent cognitive enhancement effects with better nootropic activity compared to piracetam (HY-B0585). Sunifiram is promising for research in neurodegenerative diseases such as mild cognitive impairment (MCI) and Alzheimer's disease (AD)[1][2][3][4]. In Vitro:Sunifiram (0.01-1 μM, 30 minutes) reduced the antagonistic effect of kynurenic acid on NMDA and increased NMDA activity[4]. In Vivo:Sunifiram (0.001-0.1 mg/kg, p.o. or i.v., single dose, 20 minutes prior) is able to prevent amnesia in a scopolamine (HY-N0296)-induced amnesia mouse model[4].
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