Orotidine
CAS No. : 314-50-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $320 | In-stock |
| 5mg | $1122 | In-stock |
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| 50 mg | Get quote | |
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| Cat. No. : | HY-113226 |
| M.Wt: | 288.21 |
| Formula: | C10H12N2O8 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants[1][2]. In Vitro: Extant de novo biosynthetic pathway uses Orotidine 50-monophosphate to synthesize the canonical pyrimidine nucleotides in RNA and DNA. In this context, Orotidine is the only nucleotide that is synthesized through a ‘direct intermolecular nucleosidation’ step, with an attack of the fully-preformed nucleobase (orotic acid) on the activated 5-phosphoribosyl-diphosphate as opposed to the purine nucleotides whose heterocyclic rings are constructed stepwise on the sugar[1].
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