Evans Blue
CAS No. : 314-13-6
(Synonyms: Direct Blue 53; T-1824; C.I. 23860)
| Size | Price | Stock |
|---|---|---|
| 100mg | $25 | In-stock |
| 500mg | $35 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-B1102 |
| M.Wt: | 960.81 |
| Formula: | C34H24N6Na4O14S4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 25 mg/mL;H2O : 33.33 mg/mL (ultrasonic) |
Evans Blue (Direct Blue 53) is a potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Evans Blue is a L-glutamate and kainate receptor-mediated currents inhibitor. Evans Blue has a strong affinity towards serum albumin, making it a high molecular weight protein tracer. Evans Blue is also used to study BBB (blood-brain barrier) permeability[1][2]. In Vitro:Evans blue, a bis-azo dye, is a non-permeating dye. In presence of plasma membrane damage, Evans blue enters in the cytoplasm and nucleus, thereby staining them blue. Evans blue is used for checking cell viability[1]. In Vivo:The amount of Evans Blue (2% solution; 4 mL/kg) stain accumulated in the brains of mice after ICH produced by collagenase injection was independent of the stain administration route[2].
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