[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide
CAS No. : 313988-89-5
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| Cat. No. : | HY-P1324 |
| M.Wt: | 4207.66 |
| Formula: | C183H281N57O54S2 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist with an IC50 of 0.24 nM for binding to the hY5 receptor. [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide induces a high amount of food intake[1]. In Vitro: [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide has IC50s of 530 nM, >500 nM, 51 nM for binding to the hY1, hY4, hY2 receptors[1]. In Vivo: [cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide (0.2, 2 nmol/rat) induces a high amount of food intake in a dose-dependent manner in adult male rats weighing 340-400 g[1].
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