HIF-2α-IN-3
CAS No. : 313964-19-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $350 | In-stock |
| 10mg | $550 | In-stock |
| 50mg | $1650 | In-stock |
| 100mg | $2250 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-18370 |
| M.Wt: | 335.66 |
| Formula: | C12H6ClN5O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (ultrasonic) |
HIF-2α-IN-3, an allosteric inhibitor of hypoxia inducible factor-2α (HIF-2α), exhibits an IC50 of 0.4 µM and a KD of 1.1 µM. Anticancer agent[1].
IC50 & Target: IC50: 0.4 µM (HIF-2α)[1]
KD: 1.1 µM (HIF-2α)[1]
In Vitro: HIF-2α-IN-3 (Compound 1) inhibit HIF-2α-ARNT (also known as HIF-β) heterodimerization by binding an internal cavity of the HIF-2α PAS-B domain[1].
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- Cat. No.:
- HY-18370
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