| Size | Price | Stock |
|---|---|---|
| 5mg | $60 | In-stock |
| 10mg | $82 | In-stock |
| 25mg | $139 | In-stock |
| 50mg | $188 | In-stock |
| 100mg | $255 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-19793 |
| M.Wt: | 524.23 |
| Formula: | C20H16Br2N2O3S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
RS-1 is a RAD51 activator. RS-1 enhances the homologous recombination activity of human RAD51 by promoting the formation of active presynaptic filaments[1]. IC50 & Target:RAD51[1][2] In Vitro:RS-1 is a RAD51 activator, stimulating binding of hRAD51 to DNA with Kd ranging from 48 nM to 107 nM in the presence of ATP or ADP and in the absence of a nucleotide cofactor, and such an effect is not via inhibiting its ATPase activity. RS-1 (20 μM) affects the length and helical pitch of hRAD51 protein-DNA complexes. RS-1 (0, 1, 5, 10, 15, 20, and 25 μM) stimulates strand assimilation activity of hRAD51. RS-1 (7.5 μM) promotes resistance of human cells to cross-linking chemotherapy[1]. RS-1 (0, 7.5, 15 μM) increases Cas9-mediated knock-in efficiencies in rabbit embryos[2].
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