SR31527 (chloride)
CAS No. : 311814-78-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $180 | In-stock |
| 10mg | $290 | In-stock |
| 25mg | $590 | In-stock |
| 50mg | $950 | In-stock |
| 100mg | $1540 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-118961 |
| M.Wt: | 319.81 |
| Formula: | C15H14ClN3OS |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
SR31527 chloride is a potent KIFC1 inhibitor with an IC50 value of 6.6 µM. SR31527 chloride decreases cell viability and colony formation[1].
IC50 & Target:IC50: 6.6 µM (KIFC1)[1]
In Vitro:SR31527 chloride binds to KIFC1 with a Kd value of 25.4 nM[1].
SR31527 chloride (50 µM; 24 h) induces multiple spindle formation in MDA-MB-231, BT549 and MDA-MB-435s cells[1].
SR31527 chloride (0-100 µM; 96 h, 10-12 days) decreases the cell viability and colony formation of breast cancer cells and is less cytotoxic to LL47 cells[1].
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