Glutaminase C-IN-1
CAS No. : 311795-38-7
(Synonyms: Compound 968)
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $110 | In-stock |
| 50mg | $350 | In-stock |
| 100mg | $495 | In-stock |
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| Cat. No. : | HY-12682 |
| M.Wt: | 475.42 |
| Formula: | C27H27BrN2O |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts[1][2].
IC50 & Target:Glutaminase C[2]
In Vitro:Glutaminase C-IN-1 (Compound 968) (10 μM; 14 d) inhibits cellular transformation in NIH 3T3 cells[1].
Glutaminase C-IN-1 (10 μM; 6 d) blocks the signaling activity of a specific target of Dbl[1].
Glutaminase C-IN-1 blocks the transforming activity of human breast cancer cells[1].
Glutaminase C-IN-1 (10 μM) blocks glutaminolysis in transformed cells[2].
Glutaminase C-IN-1 preferentially binds to the monomeric state of Glutaminase C[2].
In Vivo:Glutaminase C-IN-1 (Compound 968) (200 μg/mouse; i.p.; daily for 12 days) reduces tumor volume in mice[1].
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