β-NETA


CAS No. : 31059-54-8

31059-54-8
Price and Availability of CAS No. : 31059-54-8
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5mg $51 In-stock
10mg $80 In-stock
25mg $148 In-stock
50mg $240 In-stock
100mg $400 In-stock
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Cat. No. : HY-124957
M.Wt: 369.24
Formula: C16H20INO
Purity: >98 %
Solubility: DMSO : 31.25 mg/mL (ultrasonic)
Introduction of 31059-54-8 :

β-NETA is a potent and noncompetitive choline acetyltransferase (ChA; IC50=76 μM) and cholinesterase (ChE; IC50=40 µM) inhibitor. β-NETA weakly inhibits acetylcholinesterase (AChE; IC50=1 mM)[1][2]. IC50 & Target: IC50: 76 μM (ChA); 40 µM (ChE); 1 mM (AChE)[1] In Vitro: β-NETA exhibits no effects at muscarinic receptors, ganglionic nicotinic receptors, skeletal muscular nicotinic receptors, cholinesterases or carnitine acetyltransferase at concentrations which inhibits ChA. At concentrations higher than the IC50 value to inhibit ChA, β-NETA antagonizes the effect of acetylcholine (ED50=100 µM), histamine and KCl-induced contractions in the guinea pig longitudinal ileal muscle[2].

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