IMR-1


CAS No. : 310456-65-6

310456-65-6
Price and Availability of CAS No. : 310456-65-6
Size Price Stock
5mg $61 In-stock
10mg $105 In-stock
50mg $418 In-stock
100mg $693 In-stock
200 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-100431
M.Wt: 353.41
Formula: C15H15NO5S2
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 310456-65-6 :

IMR-1 is a novel class of Notch inhibitor targeting the transcriptional activation with an IC50 of 26 μM. IMR-1 prevents the recruitment of Mastermind-like 1 (Maml1) to the Notch Ternary Complex (NTC) on chromatin, inhibits Notch target gene transcription and dramatically inhibits tumor growth[1]. IC50 & Target:IC50: 26 μM (Notch)[1] In Vivo:IMR-1 (i.p.; 15mg/kg; for 28 days) inhibits Notch-dependent tumor growth in patient-derived xenograft models[1].

Your information is safe with us.