Fargesin


CAS No. : 31008-19-2

31008-19-2
Price and Availability of CAS No. : 31008-19-2
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5mg $80 In-stock
10mg $140 In-stock
20mg $230 In-stock
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Cat. No. : HY-N0719
M.Wt: 370.40
Formula: C21H22O6
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 31008-19-2 :

Fargesin is a bioactive neolignan isolated from magnolia plants, with antihypertensive and anti-inflammatory effects[1][2][3]. In Vitro: Fargesin exhibits anti-inflammation effects on THP-1 cells via suppression of PKC pathway including downstream JNK, nuclear factors AP-1 and NF-?B[3].
Fargesin as a potential β? adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis[4].
In Vivo: Fargesin has antihypertensive effect in 2K1C hypertensive rats via inhibiting oxidative stress and promoting NO release[1].

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