Tubulysin E
CAS No. : 309935-58-8
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| Cat. No. : | HY-N2346 |
| M.Wt: | 814.04 |
| Formula: | C42H63N5O9S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Tubulysin E is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range[1]. Tubulysin E is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[2].
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