6-Heptynoic acid


CAS No. : 30964-00-2

(Synonyms: Hept-6-ynoic acid)

30964-00-2
Price and Availability of CAS No. : 30964-00-2
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Cat. No. : HY-34643
M.Wt: 126.15
Formula: C7H10O2
Purity: >98 %
Solubility: DMSO : ≥ 200 mg/mL
Introduction of 30964-00-2 :

Hexanoylic acid (Hex-6-ynoic acid) is a drug intermediate. Hexanoylic acid can be functionalized by esterification reaction to paclitaxel (HY-B0015), enabling it to undergo an efficient ring addition reaction with β-cyclodextrin, thereby enhancing its water solubility, stability and targeting properties[1]. In Vitro:6-Heptynoic acid contains an alkyne group and a carboxylic acid. The terminal carboxylic acid can form an amide bond with an primary amine (activation is required). Alkynes can form triazole bonds with molecules containing azide groups through a copper-catalyzed reaction[1].

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