Crustacean cardioactive peptide,free acid


CAS No. : 309247-84-5

309247-84-5
Price and Availability of CAS No. : 309247-84-5
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Cat. No. : HY-P0303
M.Wt: 959.10
Formula: C42H58N10O12S2
Purity: >98 %
Solubility: 10 mM in H2O
Introduction of 309247-84-5 :

Crustacean cardioactive peptide,free acid is a highly conserved, amidated cyclic nonapeptide, first isolated from the pericardial organs of the shore crab Carcinus maenas, where it has a role in regulating heartbeat; Crustacean cardioactive peptide,free acid also modulates the neuronal activity in other arthropods. In Vitro: Ultrabithorax and Abdominal-A are not necessary for specification of the CCAP-interneurons, but are absolutely required to prevent the death by apoptosis of the CCAP-efferent neurons[2]. In Vivo: CCAP, FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates, increase hemolymph flow velocity in the antennal space[1].

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