Aloesin


CAS No. : 30861-27-9

(Synonyms: Aloeresin)

30861-27-9
Price and Availability of CAS No. : 30861-27-9
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5mg $70 In-stock
10mg $110 In-stock
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Cat. No. : HY-N2460
M.Wt: 394.37
Formula: C19H22O9
Purity: >98 %
Solubility: DMSO : 270 mg/mL (ultrasonic)
Introduction of 30861-27-9 :

Aloesin (Aloeresin) is a tyrosinase inhibitor, and shows anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin can induce apoptosis and be used in ovarian cancer research[1][2][3]. In Vitro: Aloesin (0-40 μM, 24, 48, and 72?h) inhibits ovarian cancer cell growth in a dose- and time-dependent manner[1].
Aloesin (0-10 μM; 48 h) arrest the cell cycle at S-phase in a dose-dependent manner in SKOV3 cells[1].
Aloesin (0-10 μM; 48 h) promotes cell apoptosis in SKOV3 cells[1].
Aloesin (0-10 μM; 48 h) inhibits the phosphorylation of the MAPK signaling pathway[1]. In Vivo: Aloesin (injection; 20?mg/kg or 40?mg/kg; once daily; 7 w) inhibits tumor growth in a Xenograft model of ovarian cancer[1].

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