TCID
CAS No. : 30675-13-9
(Synonyms: 4,5,6,7-Tetrachloroindan-1,3-dione)
| Size | Price | Stock |
|---|---|---|
| 1mg | $30 | In-stock |
| 5mg | $65 | In-stock |
| 10mg | $103 | In-stock |
| 25mg | $237 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-18638 |
| M.Wt: | 283.92 |
| Formula: | C9H2Cl4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic) |
TCID (4,5,6,7-Tetrachloroindan-1,3-dione) is a potent and selective neuronal ubiquitin C-terminal hydrolase (UCH-L3) inhibitor with an IC50 of 0.6 μM[1]. TCID diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons[2].
IC50 & Target: IC50: 0.6 μM (UCH-L3) and 75 μM (UCH-L1)[1]
In Vitro: TCID (4,5,6,7-Tetrachloroindan-1,3-dione; compound 11) inhibits UCH-L1 with an IC50 of 75 μM[1].
TCID (10 μM; 1, 2 hours) diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons[2].
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