KAAD-Cyclopamine


CAS No. : 306387-90-6

(Synonyms: Cyclopamine-KAAD)

306387-90-6
Price and Availability of CAS No. : 306387-90-6
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50μg $270 Get quote
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Cat. No. : HY-100535
M.Wt: 697.99
Formula: C44H63N3O4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 306387-90-6 :

KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist[1]. In Vitro: KAAD-Cyclopamine inhibits pathway activation induced by 1 μM purmorphamine with an IC50 of 3 nM, wheras this cyclopamine derivative has an IC50 of 100 nM in Shh-LIGHT2 cells stimulated with 10 μM purmorphamine[1].

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