Size | Price | Stock |
---|---|---|
25μg | $170 | Get quote |
50μg | $270 | Get quote |
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Cat. No. : | HY-100535 |
M.Wt: | 697.99 |
Formula: | C44H63N3O4 |
Purity: | >98 % |
Solubility: | 10 mM in DMSO |
KAAD-Cyclopamine, a hedgehog signaling inhibitor, is a smoothened antagonist[1]. In Vitro: KAAD-Cyclopamine inhibits pathway activation induced by 1 μM purmorphamine with an IC50 of 3 nM, wheras this cyclopamine derivative has an IC50 of 100 nM in Shh-LIGHT2 cells stimulated with 10 μM purmorphamine[1].
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