Perfluorodecalin
CAS No. : 306-94-5
(Synonyms: PP 5; Perfluorodecahydronaphthalene)
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| Cat. No. : | HY-108298 |
| M.Wt: | 462.08 |
| Formula: | C10F18 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C) |
Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears[1][2]. Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood[3]. Perfluorodecalin enhances bone regeneration and cell viability[4][5]. In Vitro:Perfluorodecalin prolongs the cells survival in anaerobic environment, enhances the radiopacity, injectability, cohesion of bone cements and the bone regeneration[4]. Perfluorodecalin (10% v/v) ameliorates hypoxia and increases cell viability in transplantation of encapsulated islets[5]. In Vivo:Perfluorodecalin (1.1-1.5 ml/eye) induces inflammation and retinal damage in albino rabbits[2].
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