Amezinium (methylsulfate)
CAS No. : 30578-37-1
(Synonyms: Amezinium metilsulfate; Lu-1631)
| Size | Price | Stock |
|---|---|---|
| 100mg | $60 | In-stock |
| 500mg | $84 | In-stock |
| 1g | $114 | In-stock |
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| Cat. No. : | HY-A0275 |
| M.Wt: | 313.33 |
| Formula: | C12H15N3O5S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 34 mg/mL;H2O : 50 mg/mL (ultrasonic) |
Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake. Target: alpha and beta-1 receptors Amezinium metilsulfate is a sympathomimetic drug used for the treatment of low blood pressure. Cardiovascular effects of the new sympathomimetic Amezinium metilsulphate are investigated in 25 patients compared with a control group (n = 25). During spinal/epidural anaesthesia 5 mg amezinium is given i.v. if blood pressure dropped greater than 20 mmHg. from starting-point. A significant recovery of blood pressure (epidural anaesthesia: syst 21%, diast 9%; spinal anaesthesia: syst 13%, diast 6.6%) and a decrease in heart rate (6.8% resp. 4,5%) are thought due to peripheral vasoconstriction. Amezinium proves a stimulating drug for alpha- and beta 1-receptors by stabilising the systemic blood pressure in spinal/epidural anaesthesia.
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