SANT-1 (GMP)
CAS No. : 304909-07-7
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| Cat. No. : | HY-100224G |
| M.Wt: | 373.49 |
| Formula: | C23H27N5 |
| Purity: | >98 % |
| Solubility: |
SANT-1 (GMP) is SANT-1 (HY-100224) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SANT-1, a potent Smo antagonist, inhibits Hedgehog signaling[1].
In Vitro:SANT-1 is a potent Smo antagonist, binds directly to Smo, and inhibits Hedgehog signaling, with IC50s of 20 nM and 30 nM in Shh-LIGHT2 and SmoA1-LIGHT2 cells, respectively[1].
SANT-1 (1 μM, for 24 or 48 hours) decreases the proliferation of medulloblastoma cells[2].
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