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1,2-Dipalmitoyl-sn-glycerol


CAS No. : 30334-71-5

30334-71-5
Price and Availability of CAS No. : 30334-71-5
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Cat. No. : HY-W010736
M.Wt: 568.92
Formula: C35H68O5
Purity: >98 %
Solubility: Ethanol : 5.56 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 30334-71-5 :

1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that activates PKC. 1,2-Dipalmitoyl-sn-glycerol promotes GLUT4 translocation to the cell surface and recruitment to the plasma membrane of adipocytes. 1,2-Dipalmitoyl-sn-glycerol can be used in research on type 2 diabetes[1][2][3][4][5][6][7]. In Vitro:DP-DAG (30 μM; 20 min) promotes GLUT4 translocation to the cell surface in 3T3L1-GLUT4myc adipocytes[1].
1,2-Dipalmitoyl-sn-glycerol (30 μM; 10 min) does not activate Akt in 3T3L1-GLUT4myc adipocytes[1].
1,2-Dipalmitoyl-sn-glycerol (100 μM; 5 min) activates PKCα, -βI, -βII, -γ, -δ, and -ε, but not PKCλ/ι or -ζ, in cell-free systems[1].
1,2-Dipalmitoyl-sn-glycerol (0.1-10.0 μg/mL; 24 h) does not alter cell proliferation in normal human dermal fibroblasts in vitro at doses up to 10.0 μg/mL[2].
1,2-Dipalmitoyl-sn-glycerol (1.0 μM) alone supports optimal balanced growth of Frankia strain BR[5]. In Vivo:Topically applied 1,2-dipalmitoyl-sn-glycerol (diC16) (50 mg/mL; topical; twice daily; 5 days) does not induce a significant change in skin pigmentation in guinea pigs[2].

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