| Size | Price | Stock |
|---|---|---|
| 5mg | $65 | In-stock |
| 10mg | $109 | In-stock |
| 25mg | $240 | In-stock |
| 50mg | $400 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-101454 |
| M.Wt: | 397.70 |
| Formula: | C16H10ClF6NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 150 mg/mL |
SR0987, a SR1078 analog, is a RORγt agonist, with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1[1]. IC50 & Target: EC50: 800 nM (RORγt)[1]. In Vitro: SR0987 clearly shows a concentration dependent induction of reporter gene expression with an EC50 of ~800nM. SR0987 treatment results in a statistically significant reduction of the surface expression of PD-1 whereas desmostrol treatment shows no effect. Treatment with SR0987 and or desmosterol results in a trend towards increased IL17 production[1].
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