Deoxycholic acid sodium salt


CAS No. : 302-95-4

(Synonyms: Sodium deoxycholate)

302-95-4
Price and Availability of CAS No. : 302-95-4
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Cat. No. : HY-N0593A
M.Wt: 414.55
Formula: C24H39NaO4
Purity: >98 %
Solubility: DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 302-95-4 :

Deoxycholic acid sodium salt (sodium deoxycholate), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5[1][2]. IC50 & Target:TGR5[1] In Vitro: Deoxycholic acid sodium hydrate (DCA) (100 μM) induces the production of gastric cancer cell line MGC803 resistant to acidified bile acids and enhances their survival and proliferation activity under bile acid stress[2].
Deoxycholic acid sodium hydrate (DCA) (100 μM)-induced resistant cells shows altered morphology, significantly elevated telomerase activity, better cell viability and reduces apoptosis compared to normal MGC803 cells[2].

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