Retinoic acid (GMP)
CAS No. : 302-79-4
(Synonyms: Vitamin A acid (GMP); all-trans-Retinoic acid (GMP); ATRA (GMP))
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| Cat. No. : | HY-14649G |
| M.Wt: | 300.44 |
| Formula: | C20H28O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming) |
Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6]. In Vitro:Retinoic acid (GMP) time- and dose- dependently induces differentiation of EC cells and ES cells into specific cell types[1]. Retinoic acid (GMP) induces partial differentiation of F9 embryonal carcinoma cells into endoderm cells[2]. Retinoic acid (GMP) (100 nM; 2-8 d) promotes photoreceptor differentiation in early postnatal retinal cultures[3]. Retinoic acid (GMP) (0.1 μM; 10-12 d) induces human SH-SY5Y neuroblastoma cells differentiation with long cell processes[4]. Retinoic acid (GMP) (0-10 μM; 48 h) dose-dependently induces morphologic differentiation of LA-N-1 human neuroblastoma cells[5]. In Vivo:Retinoic acid (GMP) (0.3 μM; embryos are immersed in tank water containing retinoic acid) accelerates of rod differentiation is observed following 24 and 48 hours of application in zebrafish[6].
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