Org41841
CAS No. : 301847-37-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $210 | In-stock |
| 10mg | $360 | In-stock |
| 25mg | $790 | In-stock |
| 50mg | $1280 | In-stock |
| 100mg | $2050 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-100271 |
| M.Wt: | 402.53 |
| Formula: | C19H22N4O2S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC50s of 0.2 and 7.7 μM, respectively. IC50 & Target: EC50: 0.2 μM (LHCGR), 7.7 μM (TSHR)[1] In Vitro: Functional assays demonstrate that Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC50s of 0.2 and 7.7 μM, respectively. Treatment of L570F with Org41841 reveals an improved EC50 of 800 nM. M9 responds to Org41841 with an improved EC50 of 2700 nM and a greatly improved efficacy for signaling to 99% of the maximal value observed for thyroid-stimulating hormone (TSH) stimulation of thyroid-stimulating hormone receptor (TSHR)[1].
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