GSA-10
CAS No. : 300833-95-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $120 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $420 | In-stock |
| 50mg | $700 | In-stock |
| 100mg | $1150 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-12317 |
| M.Wt: | 450.53 |
| Formula: | C26H30N2O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 1.67 mg/mL (ultrasonic;warming;heat to 60°C) |
GSA-10 is a potent smooth (Smo) receptor agonist. GSA-10 is a potent osteogenic molecule. GSA-10 can mediate Hedgehog (Hh) signaling. GSA-10 can be used in regenerative medicine for cancer disease and in the study of fat development[1][2][3].
IC50 & Target:Smoothened receptor[1]
In Vitro:GSA-10 (3 μM; 6 days) can induce cell differentiation into osteoblasts in pluripotent stromal cells C3H10T1/2 with an EC50 of 1.2 μM[1][2].
GSA-10 (10 μM; 24 h) inhibits fat formation in 3T3-L1 preadipocytes by activating the Smo-Lkb1-Ampk pathway[3].
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