OB-1
CAS No. : 300803-69-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $80 | In-stock |
| 10mg | $115 | In-stock |
| 25mg | $190 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $480 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-122671 |
| M.Wt: | 407.38 |
| Formula: | C21H17N3O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.73 mg/mL (ultrasonic;warming;heat to 60°C) |
OB-1 is a stomatin-like protein-3 (STOML3) oligomerization blocker. OB-1 is an effective inhibitor of the self-association of Stomatin, STOML1 and STOML2, but not podocin[1].
IC50 & Target:Stomatin, STOML1, STOML2, STOML3[1]
In Vitro:OB-1 (3 h) reduces mechanotransduction currents in in N2a cells with an IC50 of 10 nM[1].
In Vivo:OB-1 (250-500 pmol per paw; s.c.; once) reversibly reduces the sensitivity of mechanically gated currents in sensory neurons and silence mechanoreceptors in mice[1].
OB-1 (250 pmol per paw; s.c.; once) alleviates painful diabetic neuropathy in mice[1].
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