Sorbitol dehydrogenase-IN-1
CAS No. : 300551-49-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $720 | In-stock |
| 5mg | $1480 | In-stock |
| 10mg | $1980 | In-stock |
| 25mg | $3020 | In-stock |
| 50mg | $3980 | In-stock |
| 100mg | $5500 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-118980 |
| M.Wt: | 343.43 |
| Formula: | C17H25N7O |
| Purity: | >98 % |
| Solubility: | DMSO : 40 mg/mL (ultrasonic;warming;heat to 60°C) |
Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively. Sorbitol Dehydrogenase (SDH) is an enzyme that belongs to the zinc-containing alcohol dehydrogenase (ADH) family. ADH and ALDH are enzymes that work together to metabolize alcohol[1]. IC50 & Target:Sorbitol Dehydrogenase[1] In Vivo:Sorbitol dehydrogenase-IN-1 (compound 16) (50 µg/kg; p.o.) shows sustained inhibition of sciatic nerve fructose in chronically diabetic rats[1].
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