Muscarine
CAS No. : 300-54-9
(Synonyms: (+)-Muscarine)
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| Cat. No. : | HY-121404 |
| M.Wt: | 174.26 |
| Formula: | C9H20NO2+ |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Muscarine ((+)-Muscarine) is an agonist of prototype mAChR. Muscarine is a toxin that can stimulate the parasympathetic nervous system[1][2].
In Vitro:Muscarine (100 µM) induces an intracellular calcium signal amplitude similar to the one triggered by 10 µM acetylcholine in brain miero vascular endothelial cells (BMVECs) and brain-derived Endothelial cells.3 (bEnd.3)[1].
Muscarine (1-30 μM; 2 min) produces a dose-dependent hyperpolarization in a sub-population of the nucleus raphe magnus (NRM) cells that contain 5-hydroxytryptamine (5-HT) on the NRM neurons with an EC50 value of 2.7 µM[2].
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