6-Methylflavone


CAS No. : 29976-75-8

29976-75-8
Price and Availability of CAS No. : 29976-75-8
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Cat. No. : HY-N6630
M.Wt: 236.27
Formula: C16H12O2
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 29976-75-8 :

6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. IC50 & Target:α1β2γ2L GABAA receptor, α1β2 GABAA receptor[1] In Vitro: 6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone enhances the normal response to GABA at recombinant α1β2γ2L and α1β2 GABAA receptors (P<0.0001) at concentrations from 1 to 100 μM. 6-Methylflavone (60 μM) shifts the GABA dose-response curve to the left (n=4, F=16.38, P=0.0004), decreasing the mean EC50 at α1β2γ2L GABAA receptors by 33±5.4%[1].

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