UCB-35440


CAS No. : 299460-62-1

299460-62-1
Price and Availability of CAS No. : 299460-62-1
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1mg $3800 In-stock
5mg $7600 In-stock
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Cat. No. : HY-19443
M.Wt: 576.09
Formula: C31H34ClN5O4
Purity: >98 %
Solubility: DMSO : 20 mg/mL (ultrasonic)
Introduction of 299460-62-1 :

UCB-35440 is an orally active histamine H1 receptor antagonist and 5-lipoxygenase inhibitor. UCB-35440 can be used for the research of dermatologic inflammatory conditions[1]. In Vivo:UCB-35440 (0.3-3% w/v; topical; 2 doses) produces dose-dependent inhibition of acute PMA (HY-18739)-induced mouse ear inflammation[1].
UCB-35440 (0.3-10% w/v; topical; twice daily; 8 doses) inhibits chronic PMA-induced mouse ear inflammation[1].
UCB-35440 (10 mg/kg; oral; twice daily) significantly inhibits Histamine (HY-B1204)-induced dermal extravasation in guinea pigs[1].

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