n-Octyl β-D-glucopyranoside
CAS No. : 29836-26-8
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| Cat. No. : | HY-116285 |
| M.Wt: | 292.37 |
| Formula: | C14H28O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : 116.67 mg/mL (ultrasonic) |
n-Octyl-β-d-glucopyranoside is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins. n-Octyl-β-d-glucopyranoside can completely inhibit cavitation-induced cell lysis in vitro[1][2][3].
In Vitro:Suspensions of HL-60 cells are exposed to 1.057 MHz unfocused ultrasound for 5-15 s with various additions of alkyl glucopyranosides. 2 mM n-Octyl β-D-glucopyranoside (OGP) added to the medium resultes in 100% survival of the cells after 5 s exposure under conditions which produces 35%-100% cell lysis without the additive[3].
Variation of the concentration of n-Octyl β-D-glucopyranoside for 0.5 MPa exposure produced increased cavitation and lysis at 1 mM relative to 0 mM, but decreased cavitation at 5 mM[3].
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