CAY10444


CAS No. : 298186-80-8

(Synonyms: BML-241)

298186-80-8
Price and Availability of CAS No. : 298186-80-8
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100mg $367 In-stock
250mg $627 In-stock
1g $1265 In-stock
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Cat. No. : HY-119401
M.Wt: 287.46
Formula: C15H29NO2S
Purity: >98 %
Solubility: DMSO : 41.67 mg/mL (ultrasonic;warming;heat to 80°C)
Introduction of 298186-80-8 :

CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors[1]. In Vitro: BML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation[1].

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