1,3,5,8-Tetrahydroxyxanthone
CAS No. : 2980-32-7
(Synonyms: Desmethylbellidifolin)
| Size | Price | Stock |
|---|---|---|
| 1mg | $110 | In-stock |
| 5mg | $220 | In-stock |
| 10mg | $330 | In-stock |
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| Cat. No. : | HY-N2050 |
| M.Wt: | 260.20 |
| Formula: | C13H8O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Swertia chirata. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity[1]. In Vitro: 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells[1]. In Vivo: 1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm[1].
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