Lipofermata
CAS No. : 297180-15-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $45 | In-stock |
| 10mg | $75 | In-stock |
| 25mg | $143 | In-stock |
| 50mg | $238 | In-stock |
| 100mg | $380 | In-stock |
| 250mg | $750 | In-stock |
| 500mg | $1200 | In-stock |
| 1 g | Get quote | |
| 5 g | Get quote | |
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| Cat. No. : | HY-116788 |
| M.Wt: | 360.23 |
| Formula: | C15H10BrN3OS |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC50 of 4.84 μM in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 μM[1][2][3]. In Vitro: Lipofermata inhibits C1-BODIPY-C12 transport into C2C12, INS-1E, Caco-2 and HepG2 cells at comparable levels yielding sigmoidal dose-response curves with IC50s in the low micromolar range (IC50=2.74-39.34 μM)[2].
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