Sakuranetin


CAS No. : 2957-21-3

2957-21-3
Price and Availability of CAS No. : 2957-21-3
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1mg $52 In-stock
5mg $110 In-stock
10mg $150 In-stock
25mg $280 In-stock
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Cat. No. : HY-N3006
M.Wt: 286.28
Formula: C16H14O5
Purity: >98 %
Solubility: DMSO : ≥ 125 mg/mL
Introduction of 2957-21-3 :

Sakuranetin is a cherry flavonoid phytoalexin, shows strong antifungal activity[1]. Sakuranetin has anti-inflammatory and antioxidative activities. Sakuranetin ameliorates LPS-induced acute lung injury[2]. In Vitro: Sakuranetin (0.1 and 0.3 mM, 0-5 days post inoculation) inhibits fungal mycelium growth in potato dextrose agar[1].
Sakuranetin (0-100 μg/mL, 48 h) inhibits influenza B/Lee/40 virus replication in MDCK cells[3].
Sakuranetin (30 μM, 48 or 72 h) induces melanin synthesis, and increases the expression of Tyr, TRP1, and TRP2 in B16 melanoma cells[4].
Sakuranetin (30 μM, 12-48 h) inhibits phosphorylation of ERK and AKT in B16 melanoma cells[4].
In Vivo: Sakuranetin (20 mg/kg, intratracheal instillation, 10 μL) reduces inflammation, and reduces respiratory system elastance in an mice acute lung inflammation model induced by LPS[2].
Sakuranetin (20 mg/kg, intratracheal instillation) attenuates airway hyperresponsiveness and inflammation in Ovalbumin induced asthma murine model[5].

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