MNI-caged-L-glutamate


CAS No. : 295325-62-1

295325-62-1
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Cat. No. : HY-107520
M.Wt: 323.30
Formula: C14H17N3O6
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 295325-62-1 :

MNI-caged-L-glutamate is an inert photolabile glutamate precursor. MNI-caged-L-glutamate does not modulate NMDA and AMPA receptor function in cultured neurones. MNI-caged-L-glutamate can be used for research on neurotransmitters[1]. In Vitro:MNI-caged L-glutamate (0.1 mM; single 1 ms flashes, repeated up to 8 times) undergoes photolytic conversion with 30-38% efficiency per 1 ms flash in aqueous vesicles[1].
MNI-caged L-glutamate (250-1000 μM; 5-10 min) does not act as an antagonist at AMPARs in cultured rat hippocampal neurones, and photoreleased L-glutamate activates AMPAR-mediated currents with a half-rise time of 0.78 ms[1].
MNI-caged L-glutamate (500 μM; 5-10 min) does not act as an antagonist at NMDARs in cultured rat hippocampal neurones[1].
MNI-caged L-glutamate (1 mM; 5-10 min) does not alter GABAA R-mediated spontaneous current amplitudes in cultured rat hippocampal neurones[1].

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