Melengestrol acetate


CAS No. : 2919-66-6

2919-66-6
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Cat. No. : HY-111614
M.Wt: 396.52
Formula: C25H32O4
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 2919-66-6 :

Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2]. In Vivo: Melengestrol acetate (s.c.; 10 mg/kg; 9 days) inhibits the growth of AT3 tumors by approximately 53%. And it also causes a 54% weight reduction of the ventral prostate and a reduction of the seminal vesicles in adult male CCFl rats[1].
Melengestrol acetate (oral administration; 10 mg/kg; 24 days) causes a 58.8% Dunning R3327-AT3 tumors growth and reduces the adrenal weight by 51.6% in rat[1].

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