Meseclazone
CAS No. : 29053-27-8
(Synonyms: W2395; NSC297623)
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| Cat. No. : | HY-U00157 |
| M.Wt: | 239.66 |
| Formula: | C11H10ClNO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Meseclazone (W2395;NSC297623) exhibits inhibitory potency of secondary phase ADP aggregation. Meseclazone possesses anti-inflammatory, analgesic and antipyretic activity. In Vivo: Meseclazone inhibits collagen-induced aggregation 1 and 4 hr after oral administration[1]. Intravenous administration of Meseclazone and other nonsteroidal anti-inflammatory drugs caused a dose-dependent inhibition of bronchoconstriction resulting in the following order of descending potency: isoproterenol congruent to indomethacin greater than fenoprofen greater than tolmetin greater than aspirin greater than naproxen congruent to ibuprofen greater than phenylbutazone greater than diflunisal greater than Meseclazone greater than 5-CSA[2].
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