Ursodeoxycholic acid (sodium)


CAS No. : 2898-95-5

(Synonyms: Ursodeoxycholate (sodium); Ursodiol (sodium); UCDA (sodium))

2898-95-5
Price and Availability of CAS No. : 2898-95-5
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50mg $25 In-stock
100mg $35 In-stock
500mg $100 In-stock
1g $180 In-stock
5g $630 In-stock
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Cat. No. : HY-13771A
M.Wt: 414.55
Formula: C24H39NaO4
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C);H2O : ≥ 100 mg/mL
Introduction of 2898-95-5 :

Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2]. In Vivo: Ursodeoxycholic acid (50, 150, and 450 mg/kg; p.o.; daily for 21 days) sodium results in weight loss in C57BL/6J wildtype mice[1].

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