Carbidopa
CAS No. : 28860-95-9
(Synonyms: (S)-(-)-Carbidopa)
| Size | Price | Stock |
|---|---|---|
| 5mg | $46 | In-stock |
| 10mg | $60 | In-stock |
| 50mg | $95 | In-stock |
| 100mg | $120 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-B0311 |
| M.Wt: | 226.23 |
| Formula: | C10H14N2O4 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL;DMSO : 10 mg/mL (ultrasonic) |
Carbidopa ((S)-(-)-Carbidopa), a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth[1][2]. In Vitro:Carbidopa ((S)-(-)-Carbidopa) exhibits activities similar to that described for other AhR ligands in BχPC3 and Capan-2 cells, namely the induction of CYP1A1 and CYP1A2, which are inhibited by AhR antagonists such as CH223191[1]. In Vivo:Carbidopa also induces nuclear uptake of the AhR, and in vivo studies show that carbidopa at a dose of 1 mg/mouse significantly inhibits tumor growth in athymic nude mice bearing BχPC3 cells as xenografts[1].
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