SB-408124


CAS No. : 288150-92-5

288150-92-5
Price and Availability of CAS No. : 288150-92-5
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5mg $50 In-stock
10mg $80 In-stock
25mg $160 In-stock
50mg $270 In-stock
100mg $450 In-stock
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Cat. No. : HY-70068
M.Wt: 356.37
Formula: C19H18F2N4O
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 288150-92-5 :

SB-408124 is a non-peptide OX1 receptor antagonist with Kis of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 exhibits 50-fold selectivity over OX2 receptor[1]. In Vivo: SB-408124 (30 μg/10 μl; i.c.v.; male Wistar rats) decreases Orexin-A induced water intake in Wistar rats[2].

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