Size | Price | Stock |
---|---|---|
5mg | $100 | In-stock |
10mg | $175 | In-stock |
50 mg | Get quote | |
100 mg | Get quote | |
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Cat. No. : | HY-101448 |
M.Wt: | 398.50 |
Formula: | C17H22N2O5S2 |
Purity: | >98 % |
Solubility: | 10 mM in DMSO |
TMI-1 is a potent inhibitor of disintegrin metalloenzyme 17 (ADAM17) and other MMPs. TMI-1 inhibits LPS-induced TNF-α secretion in human primary monocytes, and human whole blood[1]. TMI-1 selectively induces caspase-dependent apoptosis in triple negative (TN) and ERBB2-overexpressing breast tumor cell lines[2].
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