Aerothionin
CAS No. : 28714-26-3
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| Cat. No. : | HY-121349 |
| M.Wt: | 818.10 |
| Formula: | C24H26Br4N4O8 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs)[1][2].
In Vitro:Aerothionin (0-100 μM, 24h) inhibits prolifeartions of pheochromocytoma cells MPC and MTT, inhibits the MTT spheroid growth (10 μM, single dose)[1].
Aerothionin (0-100 μM, 24h) exhibits toxicity in normal endothelial cells HUVECs, stimulates slightly the viability of normal fibroblasts 3T3[1].
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