Cinoxacin


CAS No. : 28657-80-9

(Synonyms: Compound 64716)

28657-80-9
Price and Availability of CAS No. : 28657-80-9
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50mg $50 In-stock
100mg $80 In-stock
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Cat. No. : HY-B1085
M.Wt: 262.22
Formula: C12H10N2O5
Purity: >98 %
Solubility: DMSO : 8.33 mg/mL (ultrasonic)
Introduction of 28657-80-9 :

Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis[1][2]. IC50 & Target: MIC: 4-64 μg/mL (Gram-negative aerobic bacteria)[2] In Vitro: Cinoxacin (0-200μg/mL approximately, 3-24 h) inhibits many gram-negative aerobic bacteria with MIC values ranging from 4 to 64 μg/mL[2]. In Vivo: Cinoxacin (Oral administration, 1.7 g/kg, treated at 1 and 5 h postinfection) is effective in experimental bacterial infections in mice, with ED50 values ranging from 8.1 to 58.6 mg/kg[2].

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