Orientin
CAS No. : 28608-75-5
| Size | Price | Stock |
|---|---|---|
| 10mg | $30 | In-stock |
| 25mg | $60 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-N0405 |
| M.Wt: | 448.38 |
| Formula: | C21H20O11 |
| Purity: | >98 % |
| Solubility: | DMSO : 31.25 mg/mL (ultrasonic) |
Orientin is a neuroprotective agentinhibits which has anti-inflammation, anti-oxidative, anti-tumor, and cardio protection properties. Orientin inhibits the levels of IL-6, IL-1β and TNF-α. Orientin increases IL-10 level. Orientin exhibits neuroprotective effect by inhibits TLR4 and NF-kappa B signaling pathway. Orientin can used in study neuropathic pain[1][2].
In Vitro:Orientin (1 µM) inhibits allergic inflammation in RBL-2H3, mBMMCs, and RPMCs cells[1].
In Vivo:Orientin (0.1–10 mg/kg for p.o.;once) inhibits allergic reaction in PCA mouse model[1].
Orientin (10–40 mg/kg for i.p.;once daily for 12 days) has an anti-neuroinflammatory effect in SNL rat model[2].
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