sn-Glycero-3-phosphocholine
CAS No. : 28319-77-9
(Synonyms: Choline Alfoscerate; Alpha-GPC; L-α-GPC)
| Size | Price | Stock |
|---|---|---|
| 25g | $28 | In-stock |
| 100g | $96 | In-stock |
| 500g | $392 | In-stock |
| 1000g | $702 | In-stock |
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| Cat. No. : | HY-17552 |
| M.Wt: | 257.22 |
| Formula: | C8H20NO6P |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : 1.43 mg/mL (ultrasonic;warming;heat to 60°C) |
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].
In Vivo: Treatment with sn-Glycero-3-phosphocholine (Choline Alfoscerate) (250 mg/kg; i.m.; daily for 3 weeks) after seizure can improve seizure-induced cognitive impairment[2].
sn-Glycero-3-phosphocholine (Choline Alfoscerate) increases the release of acetylcholine in rat hippocampus, facilitates learning and memory in experimental animals, improves brain transduction mechanisms and decreases age-dependent structural changes occurring in rat brain areas involved in learning and memory[3].
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